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Ruppert's reagent : ウィキペディア英語版
Trifluoromethyltrimethylsilane

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Trifluoromethyltrimethylsilane (often called ''Ruppert's reagent'' or ''Ruppert-Prakash reagent'') is a reagent used in organic chemistry for the introduction of the trifluoromethyl group. The compound was first prepared in 1984 in Ingo Ruppert's group at the University of Bonn and introduced into the vocabulary of organic chemistry by the group of Surya Prakash at the University of Southern California five years later.
==Use==

Upon treatment with a source of fluoride the compound forms an -ate complex that attacks aldehydes and ketones to form trifluoromethyl methanols and esters to form trifluoromethyl ketones. It is thus a substitute for trifluoromethyllithium, which, unlike higher perfluoroalkyllithium compounds, is not isolable since even at low temperature it rapidly decomposes to yield lithium fluoride and difluorocarbene.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Trifluoromethyltrimethylsilane」の詳細全文を読む



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